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產品名稱： |
鈣結合蛋白Calponin (Basic)抗體 |
| 產品型號： |
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| 產品產地： |
中國大陸 |
| 訪問次數： |
1507 |
| 發(fā)布時間： |
2016/3/29 15:37:15 |
Calponin (Basic) is an actin, tropomyosin and calmodulin binding protein
thought to be involved in the regulation of smooth muscle contraction. |
鈣結合蛋白Calponin (Basic)抗體
Clone 26A11
7 mL BOND ready-to-use PA0416 P (HIER)
Antigen Background
Calponin (Basic) is an actin, tropomyosin ａnd calmodulin binding protein
thought to be involved in the regulation of smooth muscle contraction. The
expression of basic calponin is reported to be restricted to smooth muscle
cells ａnd is a marker of the differentiated contractile phenotype of developing
smooth muscle. Vascular smooth muscle cells convert to a synthetic
dedifferentiated phenotype when this protein is lost ａnd this is a key stage in
both atherosclerosis ａnd restenosis of coronary arteries after balloon
angioplasty. It is thought that basic calponin exerts its effect via the cortical
actin cytoskeleton ａnd therefore influences proliferation, the transformed
phenotype ａnd the metastatic potential of tumor cells. Basic calponin mRNA
is expressed in smooth muscle of prostate, bowel ａnd aorta whereas neutral
and acidic calponin mRNAs are expressed in non-smooth muscle tissues
such as heart, placenta, lung, kidney, pancreas, spleen, testis ａnd ovary as
well as in smooth muscle-containing tissues.
Breast carcinoma: immunohistochemical staining with BOND ready-to-use Calponin (Basic)
(26A11) using BOND Polymer Refine Detection.
更新時間：2024/11/12 13:40:42
經營許可證號：滬寶食藥監(jiān)械經營許20220040號
標簽：鈣結合蛋白抗體 Calponin Clone 26A11
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技術支持：阿儀網， (滬)-非經營性-2022-0060總訪問量：4598951
